Lab Members - Erin Greiner

erin

Erin Greiner joined our lab in the spring of 2007. She graduated from the College of Wooster (Wooster, OH) in 2006 with a Bachelor of Arts degree in Chemistry. For her Senior Independent Study project, she worked under Dr. Virginia B. Pett on the overexpression, purification, and structural analysis of ZmHsp17.6, a small heat-shock protein from Zea Mays.

After leaving the Amish country of Ohio, Erin decided to venture off to the Hollywood Hills of UCLA where she eventually found her home in the Loo lab. Erin's research focuses on the study of huntingtin, the protein responsible for Huntington's disease (HD). In collaboration with Joseph Loo and William Yang (Neurobehavioral Genetics), Erin will use the genetic BACHD (Bacterial Artificial Chromosome Huntington Disease) mouse model coupled with proteomics and mass spectrometry analysis to study the function of the huntingtin protein in HD progression. In addition, she will investigate the protein-protein interactions with the 40kDa Huntingtin-associated protein (HAP40), examine the proteome of BACHD phospho-mimicry mutants of the N18 domain of huntingtin, and perform a global analysis of the BACHD phosphoproteome.