Lab Members - Mario Thevis


Dr. Mario Thevis came to UCLA in 2002 after receiving his Ph.D in Biochemistry at the German Sport University, Cologne, Germany under the guidance of Prof. Dr. W. Schnzer. At UCLA, Mario developed mass spectrometric methods for protein identification and characterization, including a method to selectively cleave Cys-residues. Mario published the following papers from his work at UCLA:

Benchaar SA, Xie Y, Phillips M, Ogorzalek Loo RR, Galkin VE, Orlova A, Thevis M, Muhlrad A, Almo SC, Loo JA, Egelman EH, and Reisler E. Mapping the Interaction of Cofilin with Subdomain 2 on Actin. Biochemistry 2007; 46: 225-233.

Thevis M, Loo JA, Ogorzalek Loo RR, and Schänzer W. Recommended criteria for the mass spectrometric identification of target peptides and proteins (<8 kDa) in sports drug testing. Rapid Commun Mass Spectrom 2007; 21: 297-304.

Thevis M, Ogorzalek Loo RR, and Loo JA. In-Gel Derivatization of Proteins for Cysteine-Specific Cleavages and their Analysis by Mass Spectrometry. J Proteome Res 2003; 2: 163-172.

Thevis M, Ogorzalek Loo RR, and Loo JA. Mass Spectrometric Characterization of Transferrins and their Fragments Derived by Reduction of Disulfide Bonds. J Am Soc Mass Spectrom 2003; 14: 635-647.

Daoud Kinzie S, Thevis M, Ngo K, Whitelegge J, Loo JA, and Abu-Omar MM. Posttranslational hydroxylation of human phenylalanine hydroxylase is a novel example of enzyme self-repair within the second coordination sphere of catalytic iron. J Am Chem Soc 2003; 125: 4710-4711.

Currently, Mario is a head of the Center for Preventive Doping Research, German Sport University, in Cologne. He and his wife, Nele, have a bouncing baby boy, Jan.